BREEDERVAC-IV-PLUS®

Bursal Disease, Newcastle Disease, Bronchitis, and Reovirus Vaccine

Breedervac-IV-Plus® is prepared using specific-pathogen-free (SPF) or approved substrates and contains Newcastle disease (ND) virus, Massachusetts type infectious bronchitis disease (IB) virus, 2 strains of avian reovirus (1733 and 2408), and Standard, GLS, and Delaware (A and E) strains of infectious bursal disease (IBD) virus, inactivated and suspended in the aqueous phase of an oil adjuvant emulsion.

This product has been shown to be effective for the vaccination of healthy chickens 3 weeks of age or older against Newcastle Disease, Infectious Bronchitis Virus (Massachusetts Type), tenosynovitis caused by Avian Reovirus, and to provide passive immunity against Infectious Bursal Disease (Standard; Delaware and GLS Variants) and malabsorption caused by Avian Reovirus to progeny.

  • Contains a broad range of inactivated standard and bursal-derived variant IBD and reovirus strains:
    • Induces high, uniform antibodies against IBD, ND, IB and reoviruses throughout the entire production cycle
    • Requires a small 1/2 mL dose
    • Contains exclusive immunostimulant, safe, stable oil adjuvant

  • Infectious Bronchitis (IB) – Mass type
  • Infectious Bursal disease (IBD) – Standard type
  • Infectious Bursal disease (IBD) – Del type
  • Infectious Bursal disease (IBD) – GLS type
  • Newcastle Disease (ND)
  • Tenosynovitis/Reovirus Arthritis

Many factors must be considered in determining the vaccination program for a particular farm or poultry operation. To be fully effective, the vaccine must be administered to healthy receptive birds held in proper environment under good management. In addition, the response may be modified by the age of the birds and their immune status. Seldom does 1 vaccination under field conditions produce complete protection for all individuals in a given flock. The amount of protection required will vary with the type of operation and the degree of exposure that a flock is likely to encounter.

Allow the vaccine to reach ambient temperature, 16° to 27°C (60° to 80°F), shake well before use and periodically during use. Inject 0.5 ml intramuscularly or subcutaneously in chickens using an 18-gauge x 1/2” or 1/4” needle.

It is evident that for optimal protection, preceding vaccination with live vaccines (priming) should have taken place. Generally, in flocks vaccinated with BREEDERVAC-IV-PLUS, a protective level of immunity will be achieved with only small variations between individual chickens. Revaccination during molt is recommended.

1 x 1000 doses, 500mL

  1. TO AVOID HUMAN INJECTION, EXTREME CAUTION SHOULD BE USED WHEN INJECTING ANY OIL EMULSION VACCINE. ACCIDENTAL HUMAN INJECTION MAY CAUSE SERIOUS LOCAL REACTIONS. CONTACT A PHYSICIAN IMMEDIATELY IF ACCIDENTAL HUMAN INJECTION OCCURS.
  2. Do not administer this vaccine during the critical egg laying period from onset until after peak production. Administration of this product during the lay period may result in a drop in egg production.
  3. Injection of inactivated vaccine into breast muscle may create processing plant problems under certain conditions.
  4. Ensure that vaccination equipment is clean and sterile before use.
  5. Do not use vaccination equipment with rubber parts, as the oil emulsion may attack certain types of rubber.
  6. Use entire contents when first opened.
  7. Do not vaccinate chickens within 42 days before slaughter.
  8. Store at 2° to 8°C (35° to 46°F) in the dark.
  9. Do not mix with other products.
  10. In case of human exposure, contact a physician.
  11. Contains gentamicin, neomycin and thimerosal as preservatives.
  12. FOR ANIMAL USE ONLY.

This vaccine has undergone rigid potency, safety and purity tests, and meets Merck Animal Health, U.S. and local regulatory requirements. It is designed to stimulate effective immunity when used as directed, but the user must be advised that the response to the product depends upon many factors, including, but not limited to, conditions of storage and handling by the user, administration of the vaccine, health and responsiveness of the individual chickens and the degree of field exposure. Therefore, directions should be followed carefully. A safety data sheet (SDS) is available upon request. This and any other consumer information can be obtained by calling Merck Animal Health Customer Service at 1-800-211-3573.

Keep a record of vaccine, quantity, serial number, expiration date, and place of purchase; the date and time of vaccination; the number, age, breed, and locations of chickens; names of operators performing the vaccination and any observed reactions.

Contact our sales or technical services representatives to help design a custom vaccination program.

BREEDERVAC-IV-PLUS®

Product Bulletin

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For additional information, please see the product label.
For more information regarding efficacy and safety data, go to productdata.aphis.usda.gov.

*Data on file, Merck Animal Health

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