2. MORTALITY: THE ONLY LEPTOSPIROSIS VACCINE SHOWN TO BE EFFECTIVE AGAINST DISEASE AND MORTALITY

PROTECTION FOR DOGS FACING THE MOST SEVERE CHALLENGES21

  • No dogs vaccinated with Nobivac® Canine 1-DAPPv+L₄ died or required euthanasia
  • 54% mortality and euthanasia in control groups, reflecting the severity of challenge

Clinical efficacy results showed that Nobivac® Canine 1-DAPPv+L₄ also prevented1

  • Leptospiremia
    • More than 85% of vaccinates had no leptospiremia; leptospires were cleared quickly from the blood in those that did
    • By contrast, all control dogs had leptospiremia, and it lasted significantly longer, by days
  • Liver dysfunction
    • Serum levels of bilirubin and AST* remained at normal levels in significantly more vaccinates
  • Thrombocytopenia
    • Platelet counts remained in the normal range

* AST = aspartate aminotransferase