Antibodies Induced by Repeated Borrella Burgdorferi Vaccine Administration are Not Detected in Vise-Derived C6 Peptide

Introduction

Introduction of Lyme disease vaccines for use in canines has led to the widespread use of vaccine in Lyme disease-endemic areas of the United States. The SNAP 4Dx Plus Test Kit uses 8orrelia-specific peptide (C6 peptide) for detection of antibody to 8orrelia burgdorferi. Numerous published scientific articles have documented that those immunoassays incorporating the C6 peptide as the target diagnostic antigen failed to react with sera from vaccinated dogs. The purpose of the study was to test sera from vaccinated dogs using the CG-peptide-based microtiter format ELISA and SNAP 4Dx Plus test to demonstrate that these tests are non-reactive with samples from dogs receiving repeated vaccinations. 

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