Only Nobivac vaccinates demonstrated 0% urinary shedding against all 4 serovars¹

LEPTOSPIRURIA

 

 

 

A key objective of vaccination is to prevent urinary shedding of leptospires, which has potential zoonotic risk:

• 0% of dogs vaccinated with Nobivac® Canine 1-DAPPv+L₄ developed leptospiruria

• All of the control dogs challenged with L. canicola and L. grippotyphosa, 80% of control dogs challenged with L. icterohaemorrhagiae, and 50% of control dogs challenged with L. pomona developed leptospiruria

Nobivac® Lepto₄ is shown to be effective against leptospiruria associated with
• L. grippotyphosa

• L. canicola

• L. icterohaemorrhagiae

• L. pomona

LEPTOSPIREMIA

• None of the dogs vaccinated with Nobivac® Canine 1-DAPPv+L₄ developed leptospiremia

• 100% of the control dogs challenged with L. canicola, L. grippotyphosa, L. icterohaemorrhagiae, and 75% of the control dogs challenged with L. pomona showed leptospiremia, indicating the severe challenge model