The only leptospirosis vaccine for dogs proven to be effective against disease and mortality²

EFFECTIVE AGAINST MORTALITY CAUSED BY 4 VIRULENT LEPTOSPIRA SEROVARS

• No dogs vaccinated with Nobivac® Canine 1-DAPPv+L₄ died or required euthanasia
• 54% mortality and euthanasia in control groups, reflecting the severity of challenge

Clinical efficacy results showed that Nobivac® Canine 1-DAPPv+L₄ also prevented

• Liver dysfunction
  • Serum levels of bilirubin and AST* remained at normal levels in significantly more vaccinates
• Thrombocytopenia
  • Platelet counts remained in the normal range

*AST = aspartate aminotransferase